2.3: Genetic Disorders
- Page ID
- 10182
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Recessive disorders (homozygous): the individual inherits a gene change from both parents. If the gene is inherited from just one parent, the person is a carrier and does not have the condition. | Cases per Birth |
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1 in 3500 |
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1 in 10,000 |
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1 in 4000; 1 in 30 American Jews is a carrier; 1 in 20 French Canadians is a carrier |
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Fewer than 20,000 US cases per year |
Autosomal Dominant Disorders (heterozygous): In order to have the disorder, the individual only needs to inherit the gene change from one parent. | Cases per Birth |
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1 in 10,000 |
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1 in 250 |
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1 in 15,000-40,000 |
Sex-Linked Disorders: When the X chromosome carries the mutated gene, the disorder is referred to as an X-linked disorder. Males are more affected than females because they possess only one X chromosome without an additional X chromosome to counter the harmful gene. | Cases per Birth |
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1 in 10,000 males |
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1 in 3500 males |