References
Bloomfield, Gareth, David Traynor, Sophia P. Sander, Douwe M. Veltman, Justin A. Pachebat, and Robert R. Kay. 2015. “Neurofibromin Controls Macropinocytosis and Phagocytosis in Dictyostelium.” eLife 4:e04940.
Chaix, Raphaëlle, Chen Cao, and Peter Donnelly. 2008. “Is Mate Choice in Humans MHC-Dependent?” PLoS Genetics 4 (9): e1000184.
Cook, Laurence M. 2003. “The Rise and Fall of the Carbonaria Form of the Peppered Moth.” The Quarterly Review of Biology 78 (4): 399–417.
Cota, Bruno Cézar Lage, João Gabriel Marques Fonseca, Luiz Oswaldo Carneiro Rodrigues, Nilton Alves de Rezende, Pollyanna Barros Batista, Vincent Michael Riccardi, and Luciana Macedo de Resende. 2018. “Amusia and Its Electrophysiological Correlates in Neurofibromatosis Type 1.” Arquivos de Neuro-Psiquiatria 76 (5): 287–295.
D’Asdia, Maria Cecilia, Isabella Torrente, Federica Consoli, Rosangela Ferese, Monia Magliozzi, Laura Bernardini, Valentina Guida, et al. 2013. “Novel and Recurrent EVC and EVC2 Mutations in Ellis-van Creveld Syndrome and Weyers Acrofacial Dyostosis.” European Journal of Medical Genetics 56 (2): 80–87.
Dobzhansky, Theodosius. 1937. Genetics and the Origin of Species. Columbia University Biological Series. New York: Columbia University Press.
Facon, Benoît, Laurent Crespin, Anne Loiseau, Eric Lombaert, Alexandra Magro, and Arnaud Estoup. 2011. “Can Things Get Worse When an Invasive Species Hybridizes? The Harlequin Ladybird Harmonia axyridis in France as a Case Study.” Evolutionary Applications 4 (1): 71–88.
Fisher, Ronald A. 1919. “The Correlation between Relatives on the Supposition of Mendelian Inheritance.” Transactions of the Royal Society of Edinburgh 52 (2): 399–433.
Ford, E. B. 1942. Genetics for Medical Students. London: Methuen.
Ford, E. B. 1949. Mendelism and Evolution. London: Methuen.
Grant, Bruce S. 1999. “Fine-tuning the Peppered Moth Paradigm.” Evolution 53 (3): 980–984.
Haldane, J. B. S. 1924. “A Mathematical Theory of Natural and Artificial Selection (Part 1).” Transactions of the Cambridge Philosophical Society 23 (2):19–41.
Imperato-McGinley, J., and Y.-S. Zhu. 2002. “Androgens and Male Physiology: The Syndrome of 5 Alpha-Reductase-2 Deficiency.” Molecular and Cellular Endocrinology 198 (1-2): 51–59.
Jablonski, David, and W. G. Chaloner. 1994. “Extinctions in the Fossil Record.” Philosophical Transactions of the Royal Society of London B: Biological Sciences 344 (1307): 11–17.
Livi-Bacci, Massimo. 2006. “The Depopulation of Hispanic America after the Conquest.” Population Development and Review 32 (2): 199–232.
Lombaert, Eric, Thomas Guillemaud, Jean-Marie Cornuet, Thibaut Malausa, Benoît Facon, and Arnaud Estoup. 2010. “Bridgehead Effect in the Worldwide Invasion of the Biocontrol Harlequin Ladybird.” PLoS ONE 5 (3): e9743.
Martins, Aline Stangherlin, Ann Kristine Jansen, Luiz Oswaldo Carneiro Rodrigues, Camila Maria Matos, Marcio Leandro Ribeiro Souza, Juliana Ferreira de Souza, Maria de Fátima Haueisen Sander Diniz, et al. 2016. “Lower Fasting Blood Glucose in Neurofibromatosis Type 1.” Endocrine Connections 5 (1): 28–33.
Pickering, Gary, James Lin, Roland Riesen, Andrew Reynolds, Ian Brindle, and George Soleas. 2004. “Influence of Harmonia axyridis on the Sensory Properties of White and Red Wine.” American Journal of Enology and Viticulture 55 (2): 153–159.
Repunte-Canonigo Vez, Melissa A. Herman, Tomoya Kawamura, Henry R. Kranzler, Richard Sherva, Joel Gelernter, Lindsay A. Farrer, Marisa Roberto, and Pietro Paolo Sanna. 2015. “NF1 Regulates Alcohol Dependence-Associated Excessive Drinking and Gamma-Aminobutyric Acid Release in the Central Amygdala in Mice and Is Associated with Alcohol Dependence in Humans.” Biological Psychiatry 77 (10): 870–879.
Riccardi, Vincent M. 1992. Neurofibromatosis: Phenotype, Natural History, and Pathogenesis. Baltimore: Johns Hopkins University Press.
Sanford, Malcolm T. 2006. “The Africanized Honey Bee in the Americas: A Biological Revolution with Human Cultural Implications, Part V—Conclusion.” American Bee Journal 146 (7): 597–599.
Sanna, Pietro Paolo, Cindy Simpson, Robert Lutjens, and George Koob. 2002. “ERK Regulation in Chronic Ethanol Exposure and Withdrawal.” Brain Research 948 (1–2): 186–191.
World Health Organization. 1996. “Control of Hereditary Disorders: Report of WHO Scientific meeting (1996).” WHO Technical Reports 865. Geneva: World Health Organization.
World Health Organization. 2017. “Global Priority List of Antibiotic-Resistant Bacteria to Guide Research, Discovery, and Development of New Antibiotics.” Global Priority Pathogens List, February 27. Geneva: World Health Organization. https://www.who.int/medicines/public...-ET_NM_WHO.pdf.
Wright, Sewall. 1932. “The Roles of Mutation, Inbreeding, Crossbreeding, and Selection in Evolution.” Proceedings of the Sixth International Congress on Genetics 1 (6): 356–366.
Image Descriptions
Figure 4.1: The universal ancestor (left) is depicted as a blue capsule with two tails. From it, lines branch right indicating the evolution of bacteria (top), archaea (middle), and eukarya (bottom). The bacteria branch notes “photosynthesis” and “respiration.” Archaea and Eukarya share “ribosomal RNA changed by mutation” before splitting into their two branches. The Eukarya branch also notes “nucleus and membranous organelles” and “respiration” before diverging into five separate branches with respective images of a mouse, mushroom, parasite, green algae, and a fern frond. Multicellularity is noted as independently evolving on the mouse, mushroom, and fern branches.
Figure 4.2: Snapdragons are used to illustrate phenotypes, genotypes, and alleles in a three part diagram.
Top diagram
At the top, three snapdragons are each labeled with a pair of letters:
- Red snapdragon – Two uppercase Rs
- Pink snapdragon – One upper case R and one lower case r
- White snapdragon – Two lower case rs
The set of three has two labels:
- phenotype (flower color)
- genotype (pair of alleles)
Middle diagram
A rectangle labeled “population (gene pool)” contains ten different snapdragons with corresponding genotypes: four red snapdragons (two uppercase Rs), four pink (one upper case R, one lower case r), and two white (two lower case rs).
Text on the side reads:
- Genotype frequencies (How often we note each combination: RR, Rr, or rr).
- Freq. of RR = 4/10 = 0.4
- Freq. of Rr = 4/10 = 0.4
- Freq. of rr = 2/10 = 0.2
- Allele frequencies (How often we see each allele: R or r
- Freq. of R = 12/20 = 0.6
- Freq. of r = 8/20 = 0.4
Bottom diagram
Three circles, connected by arrows, each surround a population of five snapdragons with their genotype labels (two letters for each snapdragon). A label reads: Allele frequency change is population evolution. Underneath each population is the corresponding allele frequencies.
- First population contains three red (RR), one pink (Rr), and one white (rr) snapdragons.
- Freq. R = 7/10 = 0.7
- Freq. r = 3/10 = 0.3
- Second population contains one red (RR), three pink (Rr), and one white (rr) snapdragons.
- Freq. R = 5/10 = 0.5
- Freq. r = 5/10 = 0.5
- Third population contains one red (RR), two pink (Rr), and two white (rr) snapdragons.
- Freq. R = 4/10 = 0.4
- Freq. r = 6/10 = 0.6
Figure 4.3: A capsule shaped universal ancestor is linked to a cell with smoothly rounded edges and different colored organelles by a thin black line. The line is labeled Eukarya branch (reminding the reader of Figure 4.1). Along the branch dots represent evolutionary events: ribosomal RNA changed by mutation, nucleus and membranous organelles, and respiration.
Figure 4.4: Two DNA double helix shapes are drawn. The left one, labeled “Before” shows an arrow labeled “UV radiation” pointing towards its middle. The right one, labeled “After” bulges in the middle showing that the nucleotides on the same strand have bonded together, instead of to their complements on the other strand as they should.
Figure 4.16: Three line graphs illustrate population change as a result of different types of selection. A blue line represents the original population, the red line represents the population after natural selection. While unlabeled, the X axis represents different phenotypes in the population, and the Y axis represents the frequency of each of those phenotypes. An image placed in the box of the line graph visualizes the trait being represented.
Stabilizing selection
Text reads: Robins typically lay four eggs, an example of stabilizing selection. Larger clutches may result in malnourished chicks, while smaller clutches may result in no viable offspring.
Line graph indicates a narrower range of phenotypes – or many middle sized clutches – after selection on a population with more diverse clutch sizes. Image of eggs in a nest.
Directional selection
Text reads: Light-colored peppered moths are better camouflaged against a pristine environment; likewise dark-colored peppered moths are better camouflaged against sooty environments. Thus, as the Industrial Revolution progressed in nineteenth century England, the color of the moth population shifted from light to dark, an example of directional selection.
Both the before and after population are bell-shaped curves, but the after population has shifted to the right indicating more dark-colored moths and few light-colored moths.
Diversifying selection
Text reads: In a hypothetical population, gray and Himalayan (gray and white) rabbits are better able to blend with a rocky environment than white rabbits, resulting in diversifying selection.
Image shows the before population as a bell-shaped curve with white rabbits (in the middle) as the most common. The after population shows more gray and Himalayan rabbits (the extremes on each side) as more populous than the white rabbit in the middle.