Mesoamerica was the first section of the Americas where scholars have found evidence of large settlements, agriculture, and unique cultural traditions. The Mesoamerican culture area is found in what a...Mesoamerica was the first section of the Americas where scholars have found evidence of large settlements, agriculture, and unique cultural traditions. The Mesoamerican culture area is found in what are now the modern countries of Guatemala, Mexico, Belize, El Salvador, and eastern Honduras. The region’s frequent volcanic eruptions, earthquakes, and hurricanes gave it quite a staggering amount of ecological diversity.